In this study, we analyzed the differences in the immunoreactivity of MMPs (MMP-1, 2, 7, 9, 11, 13, and 14) and TIMPs (TIMP-1, 2, and 3) in breast carcinoma representing three subtypes, luminal A, HER2-overexpressing, and basal-like, based on immunohistochemical findings. This evidence concerns the gene ERBB2 and breast carcinoma.