During the inflammatory process in rheumatoid arthritis, the axis IL-23-IL-17 appears much more important than the loop IL-12–IFN-γ, while the interaction between IL-17 and IL-23 plays an important role not only during the initial phase of inflammation, but also throughout the destructive phase marked by osteoclastogenesis [5,6]. This evidence concerns the gene IL17A and rheumatoid arthritis.