For example, IL8 expression has been shown to be under expressed in patients post imatinib treatment and miR-493-5p has been implicated in colon metastasis [35], [36], bladder cancer [37], ovarian cancer [38] and triple negative breast cancer [39]; however, the regulatory connection between this gene/miRNA pair or their functional connection to imatinib sensitivity is unknown. This evidence concerns the gene CXCL8 and ovarian carcinoma.