The mean time to diagnosis did not differ significantly between the CD group (25.32 ± 37.98 months; range: 0.1–180 months) and the CD + PRL group (33.68 ± 34.96 months; range: 0.3–120 months), and there were also no significant differences in the incidences of invasiveness or pituitary apoplexy between the two groups. The gene discussed is PRL; the disease is pituitary apoplexy.