By using deconvolution microscopy and high-resolution confocal laser scanning microscopy, we first examined the subcellular localization of GFP-tagged recombinant SYK protein in the U373 human glioblastoma cell line that was stably transfected with the eukaryotic SYK expression vector pEGFP-SYK (Fig. 1). The gene discussed is SYK; the disease is glioblastoma.