Donor mbl2 genotype was the strongest determinant of post-transplant circulating MBL levels, a not surprising finding considering that this pattern recognition molecule is produced primarily by the liver.39 MBL deficiency has been also linked to the development of sepsis in kidney or pancreas–kidney transplant recipients14, 40 or CMV infection after discontinuing valganciclovir prophylaxis.41 More studies are needed to determine the optimal cutoff levels and timing for the monitoring of this biomarker. The gene discussed is MBL2; the disease is cytomegalovirus infection.