IFNL3 and Cirrhosis: As shown in Table 2, significant factors associated RVR were young age (P = 0.032), IL28B CC genotype (P < 0.001), non-cirrhosis (P < 0.001), low viral load (P < 0.001), HCV genotype non-1 (P < 0.001), and lower NLR (P = 0.032) by univariate analysis.