Mesothelin concentrations in pleural effusions from patients with MM (28 ± 4.3 nM) were significantly higher than those from patients with benign effusions (3.2 ± 3 nM; P < 0.0001) and patients with non-MM malignancies (4.7 ± 3.9 nM; P < 0.0001) (Table 1; Figure 1). Here, MSLN is linked to Pleural effusion.