Recently, Schwarz et al. (16) have shown that T cell are the main source of IL-10 in early infection, however, BALB/c mice vaccinated with fragmented DCs that had been pulsed with L. major lysate and CpG oligodeoxynucleotides (CpG-ODN) were able to suppress IL-10 favoring the control of infection. This evidence concerns the gene IL10 and infection.