ALB and Crouzon syndrome-acanthosis nigricans syndrome: The clinical and laboratory predictors of CAN found in the studied population were age (p = 0.01), diabetes duration (p = 0.036), hypertension (p = 0.048), resting HR (p = 0.000), HbA1c (p = 0.048), urea (p = 0.000), creatinine (p = 0.008), GFR (p = 0.000), urinary albumin concentration (p = 0.000), LDL-cholesterol (p = 0.048), free T4 (p = 0.023), and hemoglobin (p = 0.01) (Table 5).