NRG1 and schizophrenia: Dysfunction in NRG1 signaling pathways has been implicated in the pathophysiology of a variety of neuropsychiatric diseases including schizophrenia (Stefansson et al., 2002; Bertram et al., 2007; Thomson et al., 2007; O'Donovan et al., 2008; Goes et al., 2009; Walker et al., 2010).