SNRK and cardiomyopathy: At a cardiac functional level, it is noteworthy that the Snrk CM-specific KO develops cardiomyopathy (Fig. 9), and assuming that this condition is metabolism-induced, we hypothesize that the CM-specific SNRK contribution will unravel in mice once they are past the neonatal stage, a development time when cardiomyopathic hearts usually switch metabolic preference from FAO back to glycolysis as a principal energy source (Akki et al., 2008; Allard et al., 1994; Kalsi et al., 1999; Kolwicz et al., 2013).