STK11 and colonic neoplasm: SNRK is a substrate for Liver kinase B1 (LKB1) via phosphorylation at threonine residue 173 (Jaleel et al., 2005), and has recently been implicated as an inhibitor of colon cancer cell proliferation (Rines et al., 2012) as well as adipocyte inflammation (Li et al., 2013).