Overall, the pattern of ZNF677 copy number aberrations was comparable to that of other genes known to be frequently inactivated by methylation in NSCLC patients (e.g. p16, RASSF1A, DAPK1, DAL-1, CDH1; supplementary Figures S3D and S3E) [8, 9, 19]. The gene discussed is CDH1; the disease is non-small cell lung carcinoma.