To investigate the biologic effect of ZNF677 expression in NSCLC cells, we stably transfected A549, NCI-H2073 and NCI-H1993 cells with a pCMV6-ZNF677 expression vector, with a pCMV6-ENTRY (empty vector) and with a pCMV6-GFP control vector. This evidence concerns the gene ZNF677 and non-small cell lung carcinoma.