A more recent report showed that miR-125a-5p plays an important role in inducing apoptosis through inhibiting the survival pathways mediated by aldehyde dehydrogenase 1a3 (aldh1a3) and myeloid leukemia–1 (mcl1) in colon cancer stem cells [44]. This evidence concerns the gene ALDH1A3 and malignant colon neoplasm.