Ten genes (ACAT1, AFF3, ANKRD55, CORO1C, FAM167A, FCGR3B, FCRL1, FCRLA, IKZF3, and TPD52) are located within RA genetic risk loci, and of these AFF3, ANKRD55, FCGR3B, FCRL1, FCRLA, and IKZF3 were reported to have additional supporting biological evidence linking them to the disease in a recent genetic and bioinformatic analysis [19]. This evidence concerns the gene AFF3 and rheumatoid arthritis.