CX3CR1 and age-related macular degeneration: Our findings also suggest a possible role for those chemokines in AMD pathogenesis, since we found a lower fraction of CX3CR1 expression on peripheral CD8+ cells in patients with neovascular AMD compared to control persons, and found that most of the patients with low expression of CX3CR1 and CCR2 on CD8+ T cells were diagnosed with AMD.