The SNPs most highly associated with increased NB susceptibility and poor outcome were found in HACE1 (rs4336470) [22], LIN28 (rs17065417) [22], [23], BARD1 (rs6435862, rs3768716) [24], LMO1 (rs110419) [25], DUSP12 (rs1027702), DDX1 (rs2619046), IL31RA (rs10055201), and HSD17B12 (rs11037575) [26]. This evidence concerns the gene HACE1 and neuroblastoma.