PTEN and glioblastoma: Through analysis of publically accessible genomic data available via the COSMIC resource, we were able to establish that point mutations of PI4K2A were rare in glioblastoma but more than 80 % of samples from a cohort of 638 exhibited loss of PI4K2A heterozygosity; this level of copy number variation mirrored that of PTEN which also localises to chromosome 10p.