VPS13A and choreatic disease: It is worth noting that mutations in another member of the VPS13 gene family (VPS13A or CHAC, MIM #605978, encoding for a protein known as Chorein), cause chorea-acanthocytosis [43] (MIM #200150), a recessive disorder of acanthocytosis and adult-onset choreic involuntary movements with significant co-morbidity with psychiatric illness [44].