GCSAM and B-cell non-Hodgkin lymphoma: GCET2 is found to be the most up-regulated genes in the more enhanced metastasis and chemoresistance cell group, and it is also known as human germinal center associated lymphoma (HGAL) gene, is specifically expressed in germinal center B-lymphocytes and germinal center-derived B cell lymphomas [12], but its function is largely unknown.