EGFR and cancer: Due to the aggressiveness of cancer cells with p53 mutation, many studies have been devoted to eradicating the mutant p53 through a variety of methods such as isolating the interaction between p53 and p63 with peptide aptamers (PA) (22), restoring the function of p53 (23), and disrupting the interaction between EGFR and colony stimulating factor 1 receptor (CSF-1R) (24).