Given that FDG and βgal-FDG mice highly express a number of known, endogenous, immunopathogenic, retinal auto-antigens (for example, IRBP, opsin, arrestin, and recoverin), but do not have an elevated frequency of one particular retinal-Ag specific Teff population, the resulting T cell-mediated autoimmunity could be directed against any of several retinal self-Ags. Here, RCVRN is linked to Autoimmunity.