On the other hand, only 29% of the disease genes that we identified were included in the multi-gene panel of Nemeth et al. (2013), including genes not previously considered to be ‘ataxia genes’, such as SPG7. Moreover, there may be limited overlap between different multi-gene panels, which are defined by specific laboratories reflecting ataxia in a given population, and based on ataxia genes known at that time. This evidence concerns the gene SPG7 and cerebellar ataxia.