TLR4 and tuberculosis: For the TLR4 gene, the SNP 672 A > C showed a χ2 test with a significant P-value (P = 0.031); the OR demonstrated a significant P-value (P = 0.012) for the CC genotype at the 672 A > C locus and a value lower than 1 (OR = 0.26, 95% CI = 0.08 to 0.80), thus indicating a significant association with resistance to tuberculosis.