Of the 40 studies on the HIF-1α C1772T polymorphism, 6 studies were conducted on prostate cancer, 6 studies on breast cancer, 3 studies on lung cancer, 4 studies on colorectal cancer, 4 studies on renal cancer, 4 studies on oral cancer and 12 studies on other cancers. The gene discussed is HIF1A; the disease is renal carcinoma.