These included 2 genes associated with long QT syndrome (types 1, 2, and 3) and Brugada syndrome (KCNQ1, KCNH2), 3 genes associated with hypertrophic and dilated cardiomyopathy (LMNA, MYBPC3, TNNI3), 1 gene associated with familial hypercholesterolemia (PCSK9), and 4 genes associated with CHD (GATA4, NKX2-5, NOTCH1, TBX1). This evidence concerns the gene NOTCH1 and coronary artery disorder.