CXCL8 and decubitus ulcer: With regards to the usefulness of PHB and PHBV as biomaterials for the regeneration of tissue, the production of IL-8,which is induced by PHB and PHBVs, may be used to improve and enhance the wound-healing process because of deficiencies of IL-8 in the wound area, particularly in problematic wounds such as burn infections and decubitus ulcer problems and in secondary wounds from systemic diseases.