According to a recent study, most of the reported pituitary carcinomas are functional (83%), with 35% of the lesions producing ACTH, 33% PRL, 9% growth hormone (GH), 4% luteinizing hormone (LH) and/or follicle-stimulating hormone (FSH), and only 1% TSH [1]. Here, POMC is linked to pituitary adenocarcinoma.