Bivariate correlations (Table 2 and Fig 2) revealedthat serum levels of leptin in PCOS women significantlycorrelated with BMI (r=0.85, p=0.001), WHR(r=0.55, p=0.01), insulin levels (r=0.85, p=0.001)and HOMA-IR (r=0.67, p=0.01). The gene discussed is INS; the disease is polycystic ovary syndrome.