A total of 40 participants with type 1 diabetes, of whom 24 were adults [mean ± standard deviation (s.d.)age 43 ± 12 years and glycated haemoglobin (HbA1c) 8.0 ± 0.9%] and 16 were adolescents (mean ± s.d. age 15.6 ± 3.6 years and HbA1c 8.1 ± 0.8%), underwent two periods of sensor‐augmented pump therapy in the home setting, in combination with or without an overnight closed‐loop insulin delivery system that uses a model predictive control algorithm to direct insulin delivery. This evidence concerns the gene INS and type 1 diabetes mellitus.