Indeed, a recent study showed that cardiovascular injury, in addition to inducing potentially cytotoxic CD8+ T cells, also promoted the release of subpopulations of T cells that expressed AT2R.25 These AT2R+ T cells were capable of producing IL-10 and were protective in another cohort of animals with myocardial infarction. The gene discussed is CD8A; the disease is myocardial infarction.