MMP23B and melanoma: This trend holds when considering only patients who had received immunotherapy after primary resection (vaccines (n = 21), immune biologics (n = 19)), where the recurrence rate was lower in patients with low melanoma MMP-23 expression (5/11; 46%) compared with patients with high melanoma MMP-23 expression (23/29; 79%) (P = 0.056) (Table 3).