LRP6 and hepatocellular carcinoma: As shown in Figure 8, miR-610 expression in 10 freshly collected HCC samples was inversely correlated with the mRNA levels of Wnt/β-catenin downstream targets, including Cyclin D1 (r = -0.842, P = 0.01), MYC (r = -0.804, P = 0.03), as well as expression of LRP6 (r = -0.805, P = 0.006) and TBL1X (r = -0.835, P = 0.024).