showed SULF2 to be a tumor growth suppressor of myeloma in vivo,27 whereas other studies showed that enhanced SULF2 expression is correlated with poor prognosis of patients with primary multiple myeloma.28 These findings might indicate that A2780cis tumors undergo constitutive self-renewal but also exhibit a slow-growing phenotype. The gene discussed is SULF2; the disease is neoplasm.