Other variants included synonymous coding variants (5), nonsynonymous coding (27 including ryr3, encoding the intracellular Ca2+ release channel ryanodine receptor 3 and Rab11fip1), knockout-equivalent nonsense (Als2 and Ttll1), essential splice site variants (3), 5′ UTR (3, including Dyx1c1, a susceptibility gene for dyslexia), 3′ UTR (9), and intronic mutations (49). The gene discussed is DNAAF4; the disease is dyslexia.