TCGA endometrial cancer data analysis (http://www.cbioportal.org/public-portal/index.do) shows that the 5p15.33 region containing both TERT and CLPTM1L is significantly amplified in ~3 % of cases (Gistic Q value <0.00011, not shown), whilst TERT and CLPTM1L mutations have been identified in a small fraction of endometrial tumours (Kandoth et al. 2013). The gene discussed is CLPTM1L; the disease is endometrial cancer.