To date, GWAS for endometrial cancer have convincingly identified evidence for endometrial cancer risk association at the HNF1B locus (Spurdle et al. 2011; Setiawan et al. 2012; Painter et al. 2014), the risk allele of which (rs4430796A) maps to a region that has also been associated with the risk of ovarian and prostate cancers (Gudmundsson et al. 2007; Shen et al. 2013; Thomas et al. 2008). This evidence concerns the gene HNF1B and Familial prostate cancer.