The third endometrial cancer risk SNP identified in this study is in the upstream/promoter region of CLPTM1L, ~60 kb away from TERT, and which also harbours several cancer risk alleles, mostly for non-hormone-related malignancies such as lung, bladder and pancreatic cancers (Haiman et al. 2011; Kote-Jarai et al. 2011, 2013; McKay et al. 2008; Petersen et al. 2010; Rafnar et al. 2009; Shete et al. 2009; Stacey et al. 2009; Turnbull et al. 2010; Wang et al. 2014). Here, CLPTM1L is linked to cancer.