HMG20B and cancer: We find that C-terminal HMG20b fragments spanning aa 173–276 and 173–264 (which lack a short stretch of residues at the very C-terminal region), as well as a cancer-associated mutation HMG20b mutant, A247P, not only fail to restore cytokinesis in HMG20b-depleted cells but also provoke defective cytokinesis even when endogenous wild-type HMG20b is present.