HIF-1α and TFE3 staining were located mostly in the nuclear of the AdCC tumor cells as compared with PA (Figs. 3 and 4A, P<0.01 for HIF-1α and P<0.001 for TFE3) and NSG (Figs. 3 and 4A, P<0.01 for HIF-1α and P<0.001 for TFE3). Here, TFE3 is linked to neoplasm.