The strongest associated DMR in the schizophrenia group was found upstream of the tRNA pseudouridine synthase 3 gene (PUS3), in the BD group was upstream of the melanin-concentrating hormone receptor 1 gene (GPR24), and in the major psychosis group it was found in the promoter region of ST6GALNAC1. ST6GALNAC1 encodes a protein involved in glycosylation and cell-cell interactions, and the identified epigenetic change overlapped a previously reported rare genomic duplication observed in schizophrenia. This evidence concerns the gene MCHR1 and schizophrenia.