We found that the genes targeted by these miRNAs, as well as the genes targeted by miRNAs outside of the 22q11.2 region yet predicted to be dysregulated because of the DGCR8 hemizygous deletion (21), were significantly represented in a protein interaction network composed of schizophrenia candidate genes (40, 41) and brain-specific interaction partners. Here, DGCR8 is linked to schizophrenia.