A univariate analysis for OS showed that age (per 1 year: hazard ratio [HR] 1.05), sex (male vs. female: HR 2.71), smoking status (ever/current vs. never: HR 1.16), preoperative serum CEA level (>5 vs. ≤5: HR 2.56), histology (SQ vs. AD: HR 2.3, others vs. AD: HR 2.16), p-stage (stage II vs. stage I: HR 2.12, stage III vs. stage I: HR 2.99), adjuvant therapy (Yes vs. No: HR 0.56), and blood group (group A vs. group O: HR 1.88) were significant prognostic factors (Table 2). This evidence concerns the gene CEACAM5 and Alzheimer disease.