While all MMPs served as good predictors of disease, as assessed using area under the receiver operating characteristic curve (AUC) (see Table 1), MMP-7 and MMP-12 are perfect classifiers (MMP-7: AUC = 0.97, sensitivity = 90%, specificity = 100% MMP-12: AUC = 1, sensitivity = 100%, specificity = 100%), suggesting them as meaningful diagnostic biomarkers in pancreatic cancer. This evidence concerns the gene MMP7 and familial pancreatic carcinoma.