Moreover, patients with other autoimmune diseases showed also increased PA28γ levels, in rheumatoid arthritis (RA) 26.9% (28/104), in different connective-tissue diseases (CTD) 25.8% (17/66) and in AOSD (adult-onset Still’s disease) 13.3% (2/15). This evidence concerns the gene PSME3 and autoimmune disease.