The majority of the patients had mixed pathology including AD and LBD (n = 6), AD and medial temporal lobe pathology (MTLP: TDP-43 proteinopathy, argyrophilic grain disease and hippocampal sclerosis) (n = 5), and AD and DLB and MTLP (n = 4). The gene discussed is TARDBP; the disease is Lewy body dementia.