The pro-apoptotic factor Bim, which can participate in both apoptosis and autophagy (assisted by dynein) [38], [39], [43], [45] appears to perform none of these biological functions in this mechanism of action and thus does not influence the inhibition of autophagy activation or the programmed cell death triggered by the recombinant protein in the studied tumor cells. The gene discussed is BCL2L11; the disease is neoplasm.