Similar to previous studies, we also observed pleiotropy for a number of loci in particular PTPN22 for JRA, T1DM, and Thyroiditis, IL5 for Eosinophilia, Asthma, and EoE and NDFIP1 for Mental Retardation traits and Cerebral Palsy. This evidence concerns the gene NDFIP1 and type 1 diabetes mellitus.