CYFIP1 and fragile X syndrome: Therefore, in a condition such as FXS, in which Fragile X Mental Retardation (FMR1), EIF4E, or Cytoplasmic FMR1-interacting Protein 1 (CYFIP1) are mutated, the complex's capacity for translation suppression is reduced and precocious induction and differentiation occur due to the lower threshold requirement that gradients of neural inducing factors must achieve (Storey, 2003; Castrén et al., 2005).