Recently, considerable attention has been focused on NAMPT (Figure 4) as a potential therapeutic target, since several reports have shown its overexpression in several kinds of73, 74 and, conversely, its downregulation by genetic or chemical means suppresses tumor cell growth in vitro and in tumor xenografts as well.75, 76, 77 One of the most widely used inhibitors of NAMPT is FK866, which is under development as an anticancer drug.24, 78. Here, NAMPT is linked to neoplasm.