The immune system responds, regardless of the cause of sepsis, by secreting inflammatory cytokines (for example, interleukin (IL)-6 and IL-10), dysregulation of which may lead to organ failure and death.4 The innate immune system through Toll-like receptors (TLRs) recognize a variety of pathogen-breakdown products such as peptidoglycans, lipopeptides and lipopolysaccharides (LPS) and so on. This evidence concerns the gene IL10 and Sepsis.