In comparing the laboratory parameters in pSS patients with and without whole salivary anti-SSA/B antibodies, we found that three laboratory parameters were significantly (p<0.05) higher in anti-SSA-positive patients than in anti-SSA-negative patients; namely, serum anti-SSA, serum anti-SSB, and immunoglobulin G. In addition, four laboratory parameters were significantly higher in pSS patients with than in those without anti-SSB antibodies; namely, serum anti-SSA, serum anti-SSB, ANA, and RF. This evidence concerns the gene BTG3 and peeling skin syndrome.